Understanding "half-life" of a benzo
The different benzos are all given different half lives in the Ashton Manuals. I understand this to mean the length of time it takes a pharm to peak in our bodies, and also how long it stays in our...
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The half life means that after this time, half of the substance has been converted or removed from the body.
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Lilly writes:I understand this to mean the length of time it takes a pharm to peak in our bodies.......................Half-life is the amount of amount of time required for the plasma concentration...
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Come on Op,I don't think Lilly wanted the mathmatical details!
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Lilly, Klonopin and Xanax are really different drugs and may affect people very differently, quite independent of their different half-lifes. It is not clear at all that a shorter half-life results in...
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Op, the math you present applies only to certain drugs but not others. Some drugs are eliminated by the body at a constant rate independent of concentration while others are not. Still others exhibit...
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Many people say that body weight must be taken in to account when prescribing doses, and presumably it effects the half life too. Any comments folk.Freddie.
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Jim wrote:Op, the math you present applies only to certain drugs but not others................Yes, but it applies to drugs that use the term "half-life" - which is the basis for the original...
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Op, all drugs use the term, "half-life." But not all follow the exponential curve you provided.Jim
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Could you give me your views on my question Jim, please, I really do want to know. Thanks.Freddie.
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freddie, body weight affects drugs in complex ways. Most drugs are intended for specific targets within the body. Some of those targets are pretty much the same size in a large person as in a small...
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jchinnis writes:Op, all drugs use the term, "half-life." But not all follow the exponential curve you provided......................Drugs whose plasma concentration does not decay exponentially should...
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Op, I guess it is a matter of precision. Drug elimination can follow a curve with two separate parts. One part can have a constant rate of elimination irrespective of current concentration, the other...
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Thanks Jim, there is a question of how important body wieght is over here.freddie.
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Thanks Jim, there is a question of how important body wieght is over here.------------------------------------------------------- Love ya,R
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Again, an interesting answer by Op, and he accounted the formulas for dose accumulation also. You must have done chemistry higher ? :)
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Thanks folks for the responses! (yes, Ronnald you are correct, tho i did find Ops comment entertaining)Jim said:"Klonapin and Xanax are really different drugs and may affect people very differently,...
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Lilly, I've seen the argument made both ways re dependence on short- vs long-halflife benzos. None of the arguments make sense to me.As to why Klonopin and Xanax might differ besides their half life...
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Lilly, there is also Xanax XR out on the market. I don't know what the half life of XR vs regular Xanax is though.
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guangs wrote:You must have done chemistry higher ? :) .......................Does that mean higher education or something else? My training is as an engineer. Engineers are trained to think logically...
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